Every recommendation is grounded in current evidence.

The gold standard of systematic reviews. Cochrane Reviews synthesise all available RCTs on a given intervention with rigorous, transparent methodology. Ready2Med uses them to weigh comparative effectiveness of treatments (manual therapy, therapeutic exercise, drugs, surgery) in musculoskeletal care.

The U.S. National Library of Medicine database — over 36 million biomedical references. It's our starting point for identifying the latest guidelines (NICE, AAOS, ISPRM, SNLG-ISS) and primary trials cited by our algorithm.

The database dedicated to physiotherapy research. Every trial is rated on the PEDro Scale (0-10) for methodological quality. Essential when the AI compares the effectiveness of manual therapy, exercise, electrotherapy or integrated approaches for musculoskeletal conditions.

Evidence-based search engine indexing clinical guidelines, systematic reviews and primary articles filtered for clinical practice. Useful for stratifying recommendations by level of evidence (I-IV).

Complementary to PubMed, with stronger European coverage and journals in rehabilitation, orthopaedics and rheumatology. Useful to catch trials and reviews published outside the US.

The UK guidelines are among the most cited worldwide for low back pain, neck pain, osteoarthritis and chronic musculoskeletal conditions. E.g. NG59 (Low back pain and sciatica).

Ready2Med adapts recommendations to the patient's country by selecting national reference guidelines: SNLG-ISS for Italy, Haute Autorité de Santé for France, American Academy of Orthopaedic Surgeons / American Physical Therapy Association for the US, DEGAM for Germany.